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The Pachter Lab Github Organization

Open source software
  • concordex: Quantitative assessment of single-cell RNA-seq clustering (Python)
  • concordexR: Quantitative assessment of single-cell RNA-seq clustering (R)
  • ffq: Find sequencing data and metadata from public databases
  • gget: Efficient querying of genomic reference databases
  • kallisto: Pseudoalignment for mapping sequence reads to targets, including quantification bulk and single-cell RNA-seq data
  • kb-python: Wrapper for the kallisto | bustools workflow for single-cell RNA-seq preprocessing
  • kite: Fast and accurate preprocessing of feature barcode experiments
  • metakallisto: metagenomics analysis with kallisto
  • monod: Fit chemical master equation models to sequencing data
  • PCCA: Couple PCA to CCA
  • seqspec: A machine-readable YAML file format for genomic library sequence and structure
  • SpatialFeatureExperiment: Extension of SpatialExperiment with sf
  • sleuth: Differential analysis of bulk RNA-seq
  • splitcode: Flexible and efficient preprocessing, parsing, and manipulation of sequencing reads
  • qcbc: Quality control synthetic barcode sequences for orthogonal sequencing-based assays
  • voyager: Platform for exploratory spatial single-cell genomics data analysis
Open source hardware
  • poseidon: Open source syringe pumps and microscope
  • colosseum: Open source fraction collector
Article repositories
These repositories contain code to reproduce figures and results from papers. Each repository has the naming convention [initials of author last names in order of appearance in the article]_[year published].

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  1. kallisto kallisto Public

    Near-optimal RNA-Seq quantification

    C 655 172

  2. kb_python kb_python Public

    A wrapper for the kallisto | bustools workflow for single-cell RNA-seq pre-processing

    Python 150 23

  3. ffq ffq Public

    A tool to find sequencing data and metadata from public databases.

    Python 549 47

  4. gget gget Public

    🧬 gget enables efficient querying of genomic reference databases

    Python 940 74

  5. sleuth sleuth Public

    Differential analysis of RNA-Seq

    R 304 95

  6. BI-BE-CS-183-2023 BI-BE-CS-183-2023 Public

    Introduction to Computational Biology and Bioinformatics Course at Caltech, 2023

    Jupyter Notebook 436 70

Repositories

Showing 10 of 133 repositories
  • FGP_2024 Public
    pachterlab/FGP_2024’s past year of commit activity
    Jupyter Notebook 4 0 2 0 Updated Oct 30, 2024
  • gget Public

    🧬 gget enables efficient querying of genomic reference databases

    pachterlab/gget’s past year of commit activity
    Python 940 BSD-2-Clause 74 16 2 Updated Oct 29, 2024
  • voyager Public

    From geospatial to spatial -omics

    pachterlab/voyager’s past year of commit activity
    R 75 Artistic-2.0 9 11 0 Updated Oct 29, 2024
  • SpatialFeatureExperiment Public

    Extension of SpatialExperiment with sf

    pachterlab/SpatialFeatureExperiment’s past year of commit activity
    R 41 Artistic-2.0 7 21 0 Updated Oct 29, 2024
  • kb_docs Public
    pachterlab/kb_docs’s past year of commit activity
    Python 1 BSD-2-Clause 0 0 0 Updated Oct 29, 2024
  • CGCCP_2023 Public

    scVI extension for unspliced RNA

    pachterlab/CGCCP_2023’s past year of commit activity
    Jupyter Notebook 16 BSD-2-Clause 1 0 0 Updated Oct 28, 2024
  • monod Public

    The Monod package fits CME models to sequencing data.

    pachterlab/monod’s past year of commit activity
    Python 29 BSD-2-Clause 3 3 0 Updated Oct 26, 2024
  • monod_examples Public

    Tutorials for the Monod package, which fits CME models to sequencing data.

    pachterlab/monod_examples’s past year of commit activity
    Jupyter Notebook 6 BSD-2-Clause 1 2 0 Updated Oct 25, 2024
  • SHSOHMP_2024 Public

    Code for reproducing the results in the second version of the preprint "Accurate quantification of single-nucleus and single-cell RNA-seq transcripts"

    pachterlab/SHSOHMP_2024’s past year of commit activity
    C++ 5 BSD-2-Clause 1 0 0 Updated Oct 25, 2024
  • LSCHWCP_2023 Public

    Identification of viral RNA in single-cell RNA sequencing data

    pachterlab/LSCHWCP_2023’s past year of commit activity
    Jupyter Notebook 2 BSD-2-Clause 1 2 0 Updated Oct 24, 2024